Vermilion Manhattan

Chill an Old Fashioned glass in preparation for serving the cocktail.

Combine the straight rye whiskey, bittersweet orange-red aperitivo, Italian red bitter liqueur, and Peychaud's or other Creole-style bitters in a mixing glass.

Add ice to the mixing glass and stir the mixture until well-chilled.

Strain the cocktail into the pre-chilled Old Fashioned glass filled with fresh ice, ideally using a large cube or a chunk of block ice.

Express the oils from an orange zest twist over the cocktail, then discard the twist.

Garnish with an orange slice wheel, and serve immediately.